A programme for ageing research with worms

Luyten W, and 19 other authors including AML. 2016. Ageing with elegans: a research proposal to map healthspan pathways. Biogerontology  7: 71–782

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Posted in ageing, metabolism, peer-reviewed articles, Uncategorized

Mutational metabolomics

Davies SK, Leroi AM, Burt A, Bundy JG, Baer CF. 2016. The mutational structure of metabolism in Caenorhabditis elegans.  Evolution 70: 1558-564

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Posted in general evolution, metabolism, mutants & variants, peer-reviewed articles, Uncategorized

State-of-the-art-metabolomics for worms

Geier FM, Fuchs S, Valbuena G, Leroi AMBundy JG. 2013. Profiling the metabolic signature of senescence. Methods in Molecular Biology 965:355-37

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Posted in ageing, metabolism, peer-reviewed articles

Methods to age worms by

Davies SK, Leroi AM, Bundy JG. 2012. Fluorodeoxyuridine affects the identification of metabolic responses to daf-2 status in Caenorhabditis elegans. Mechanisms of Ageing and Development. 133: 46-49

 

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Posted in ageing, metabolism, peer-reviewed articles

A microfluidic worm-sorter

Casadevall i Solvas X, Geier FM, Leroi AM, Bundy JG, Edel JB, deMello, AJ 2011 High-throughput age synchronisation of Caenorhabditis elegans. Chem Comm DOI: 101039/c1cc14076k

 

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Posted in ageing, metabolism, peer-reviewed articles

Metabolomic methods

Geier FM, Want EJ, Leroi AM, Bundy JG. 2011. Cross-Platform Comparison of Caenorhabditis elegans. Tissue Extraction Strategies for Comprehensive Metabolome Coverage. Anal Chem. 83:3730-3736

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Posted in metabolism, peer-reviewed articles

Metabolomics of ageing in worms

Fuchs S, Bundy JG, Davies SK, Bundy J, Leroi AM. 2010. A metabolic signature of long life in Caenorhabditis elegans. BMC Biology 8: 2

 

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Posted in ageing, metabolism, peer-reviewed articles

The balloon hypothesis

Swire J, Fuchs S, Bundy JG, Leroi AM. 2009. The cellular geometry of growth drives the amino acid economy of Caenorhabditis elegans. Proc Biol Sci B. 276:2747-54

 

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Posted in growth, metabolism, peer-reviewed articles